Session 3C: Tools for the synthetic biology of antibiotic production
09.00 - 11.00
Chair: Marnix Medema, Max Planck Institute for Marine Microbiology
09.00 - 09.30 Kirsten Jung, LMU Munich, Germany
Polyproline proteins and translational constraints
09.35 - 09.45 Tilmann Weber, Technical University of Denmark, Denmark
The promiscuous discrete acyltransferase KirCII - a novel tool for polyketide
09.50 - 10.00Derek Mattern, Friedrich Schiller University of Jena, Germany
Bioprospecting of Secondary Metabolites by Use of a Heterologous Expression System in Eukaryotes
10.05 - 10.15 Manuel Montalbán-Lopez, University of Groningen, Netherlands
Awakening sleeping lantibiotics: in vivo production of active lantibiotics
10.20 - 10.30 Youming Zhang, Shandong University, China
Direct Cloning – A new strategy for studying the PKS/NRPS gene clusters presented in bacterial genomes
10.35 - 10.45 Wade Winkler, The University of Maryland, US
Novel genetic regulatory tools for improved heterologous expression of secondary metabolite pathways
10.50 - 11.00 Sergey Zotchev, Norwegian University of Science and Technology, Norway
Engineering of a Streptomyces chassis for heterologous production of terpenoids
11:00 - 11.30 Coffee break
Session 4A: Industrial and clinical applications of synthetic biology of antibiotic production – current status and future trends
11.30 - 12.45
Chair: Maggie Smith, University of York, UK
11.30 - 12.00 Jutta Heim, Evolva SA, Switzerland
A Yeast Synthetic Biology Platform Generates Novel Pharmacological Scaffolds for Drug Discovery
12.05 - 12.15 Nick Allenby, Newcastle University, UK
Discovery and heterologous expression of antibiotics from an Amycolatopsis Isolate
12.20 - 12.30 Sarah Shepherd, University of Manchester, UK
Natural products discovery and bioengineering network
12:45 Lunch
Session 4B: Industrial and clinical applications of synthetic biology of antibiotic production – current status and future trends
15.00 - 17.10
Chair: Sergey Zotchev, Norwegian University of Science and Technology, Norway
15.00 - 15.10 Jens Schrader, DECHEMA Research Institute, Germany
Pseudomonas putida as a novel cell factory for the production of antimicrobial monoterpenoids
15.15 - 15.25 Cees van den Hondel, University of Leiden, Netherlands
Cell wall stress induced genesas new targets for antifungals in Aspergillus fumigatus
15.30 - 15.40 Mahadevan Radhakrishnan, University of Toronto, Canada
Engineering Yeast for Antibiotic Production
15.45 - 15.55 Christian Weyler, Saarland University, Germany
Synthesis of luminmides using permeabilized cells
15.55 - 16.25 Coffee break
16.25 - 16.35 Vera Meyer, Berlin University of Technology, Germany
Aspergillus niger as production host for secondary metabolites
16.40 - 17.10 Wilfried Weber, University of Freiburg, Germany